Table 2 Meta-analysis results of continuous variable

Demographical characteristics

 Age (years)

15

5.76 (3.43, 8.09)

 < 0.00001*

Clinical manifestations

 Respiratory rate (breaths/min)

3

2.14 (− 1.23, 5.51)

0.21

 Heart rate (beats/min)

3

1.37 (− 6.03, 8.78)

0.72

 Body temperature (°C)

2

 − 0.35 (− 0.71, 0.01)

0.05

 MAP (mmHg)

2

 − 8.24 (− 23.80, 7.32)

0.3

 Urine output (mL)

2

 − 355.79 (− 834.27, 122.70)

0.15

Laboratory results

 WBC count (× 10⁹/L)

5

 − 0.04 (− 5.34, 5.26)

0.99

 Platelet count (cells/mm³)

4

 − 8.79 (− 19.23, 1.66)

0.10

 CRP (mg/L)

3

33.09 (3.01, 63.18)

0.03*

 Hemoglobin (g/L)

3

 − 2.86 (− 10.78, 5.06)

0.48

 Albumin (g/L)

4

 − 5.17 (− 7.09, − 3.25)

 < 0.00001*

 AST (U/L)

2

25.80 (− 48.11, 99.72)

0.49

 Scr (mmol/L)

4

67.77 (47.21, 88.34)

 < 0.00001*

 BUN (mmol/L)

4

6.26 (1.49, 11.03)

0.01*

 Potassium (mmol/L)

2

0.33 (− 0.22, 0.88)

0.24

 PaO₂/FiO₂

5

 − 55.05 (− 60.11, − 50.00)

 < 0.00001*

 Arterial blood PH

2

 − 0.09 (− 0.15, − 0.04)

0.0005*

Long-term prognosis outcomes

 Length of hospital stay (days)

4

0.49 (− 2.09, 3.08)

0.71

 Length of ICU stay (days)

2

 − 0.09 (− 8.67, 8.48)

0.98