From: Predictors of mortality in severe pneumonia patients: a systematic review and meta-analysis
Subgroup variables | No. of studies | OR (95% CI) | Measure of heterogeneity | |
---|---|---|---|---|
P | I2 | |||
Geographic region |  | 5.30 (2.96, 7.65) |  < 0.00001 | 0.92 |
Africa | 3 | 8.75 (3.13, 14.38) | 0.002 | 0.62 |
Asia | 6 | 2.92 (0.51, 5.33) | 0.02 | 0.88 |
Europe | 2 | 7.43 (4.82, 10.04) |  < 0.00001 | 0.56 |
North America | 2 | 4.69 (− 0.89, 10.27) | 0.10 | 0.45 |
Study design | 6.36 (3.41, 9.31) |  < 0.0001 | 0.96 | |
Retrospective | 8 | 7.00 (2.52, 11.47) | 0.0002 | 0.58 |
Prospective | 6 | 5.42 (2.47, 8.37) | 0.003 | 0.93 |
ICU admission | 6.36 (3.41, 9.31) |  < 0.0001 | 0.73 | |
ICU | 7 | 5.86 (1.20, 10.51) |  < 0.0001 | 0.96 |
Not ICU | 8 | 6.80 (3.40, 10.21) | 0.01 | 0.93 |
Sex ratio (male/female) | 6.12 (3.10, 9.15) |  < 0.0001 | 0.93 | |
 ≤ 2 | 7 | 7.21 (2.62, 11.80) | 0.002 | 0.83 |
 > 2 | 7 | 5.10 (0.75, 9.45) | 0.02 | 0.96 |
Sample size | 6.12 (3.10, 9.15) |  < 0.0001 | 0.93 | |
 ≤ 100 | 5 | 5.79 (0.43, 11.15) | 0.03 | 0.80 |
100 ~ 200 | 5 | 8.37 (5.09, 11.65) |  < 0.00001 | 0.70 |
 > 200 | 4 | 3.31 (− 0.42, 7.03) | 0.08 | 0.86 |