Table 2 Search strategy

Pubmed

14–01-2025

(((((((((((synthetic) AND (lethality)) OR (synthetic lethal mutations)) AND (neoplasms)) AND (DNA repair)) OR (DNA repair deficiency disorders))) OR (crisprassociated protein 9)) OR (crisprcas systems)) OR (crispri screens)) OR (Antitumor Drug Screening Assays)) OR (RNA interference)

Scopus

14–01-2025

(TITLE-ABS-KEY (synthetic AND lethality OR synthetic AND lethal AND mutations) AND TITLE-ABS-KEY (neoplasms) AND TITLE-ABS-KEY (dna AND repair OR dna AND repair AND deficiency AND disorders) OR TITLE-ABS-KEY (crispr AND associated AND protein 9 OR crispr AND cas AND systems OR crispr AND screens) OR TITLE-ABS-KEY (drug AND screening AND assays, AND antitumor) OR TITLE-ABS-KEY (rnai) AND TITLE-ABS-KEY (cancer))

Embase

14–01-2025

((“synthetic lethality”/exp OR “synthetic lethality” OR “synthetic lethal mutation”/exp OR “synthetic lethal mutation”) AND (“neoplasm”/exp OR “neoplasm”) AND (“dna repair”/exp OR “dna repair” OR “disorders of dna synthesis and repair”/exp OR “disorders of dna synthesis and repair”) OR “crispr associated protein”/exp OR “crispr associated protein” OR “crispr cas system”/exp OR “crispr cas system” OR “crispr screens” OR ((“crispr”/exp OR crispr) AND screens) OR “drug screening”/exp OR “drug screening”) AND (“rnai”/exp OR “rnai”) AND (“malignant neoplasm”/exp OR “malignant neoplasm”)

Web of Science

14–01-2025

(((((((((((synthetic) AND (lethality)) OR (synthetic lethal mutations)) AND (neoplasms)) AND (DNA repair)) OR (DNA repair deficiency disorders))) OR (crisprassociated protein 9)) OR (crisprcas systems)) OR (crispri screens)) OR (Antitumor Drug Screening Assays)) OR (RNA interference)