Table 3 GRADE assessment of the predictive value of endocan in different medical conditions
From: The predictive value of endocan as a novel biomarker: an umbrella study on meta-analyses
Quality assessment | Quality | ||||||
|---|---|---|---|---|---|---|---|
No of studies | Design | Risk of bias | Inconsistency | Indirectness | Imprecision | Other considerations | |
Diabetes mellitus | |||||||
24 | Observational studies | No serious risk of bias | Serious | No serious indirectness | No serious imprecision | Strong association | Low |
Overall survival of cancers | |||||||
14 | Observational studies | No serious risk of bias | No serious inconsistency | No serious indirectness | No serious imprecision | Strong association | Moderate |
Recurrence-free survival of cancers | |||||||
3 | Observational studies | No serious risk of bias | No serious inconsistency | No serious indirectness | No serious imprecision | None | Low |
Hypertension | |||||||
20 | Observational studies | No serious risk of bias | Serious | No serious indirectness | No serious imprecision | Reporting bias very strong association | Low |
Preeclampsia | |||||||
3 | Observational studies | No serious risk of bias | Serious | No serious indirectness | No serious imprecision | None | Very low |
Coronary artery disease | |||||||
8 | Observational studies | Serious | Very serious | No serious indirectness | No serious imprecision | Very strong association | Very low |
Coronary slow flow | |||||||
3 | Observational studies | Serious | No serious inconsistency | No serious indirectness | No serious imprecision | None | Very low |
Sepsis mortality | |||||||
6 | Observational studies | Serious | Serious | No serious indirectness | No serious imprecision | Very strong association | Â Low |
Sepsis multiple organ dysfunction syndrome | |||||||
3 | Observational studies | Serious | Very serious | No serious indirectness | No serious imprecision | Very strong association | Very low |
Sepsis respiratory failure | |||||||
3 | Observational studies | Serious | Serious | No serious indirectness | No serious imprecision | Very strong association | Low |
Chronic kidney disease | |||||||
20 | Observational studies | No serious risk of bias | Very serious | No serious indirectness | No serious imprecision | Strong association | Very low |
COVID-19 | |||||||
11 | Observational studies | No serious risk of bias | very serious | No serious indirectness | No serious imprecision | Strong association | Very low |
Obstructive sleep apnea | |||||||
12 | Observational studies | Serious | Very serious | No serious indirectness | No serious imprecision | Strong association | Very low |